Chemical & Biomolecular Engineer · Systems Engineer · Computational Scientist

Different systems.
The same curiosity.

I came to biological modeling through chemical engineering, process dynamics, and control. The systems changed. The questions kept connecting: what is the problem? What can we measure, what can we infer? What can we design, how do we design, and what should we do next?

Today, I work at the intersection of first-principles models, scientific AI, and research software in Chemical & Biomolecular Engineering at the University of Nebraska–Lincoln.

Why systems engineer?

I use systems engineering as an organizing description of my approach: understanding interactions, linking measurements to models, testing assumptions, and designing useful interventions. My formal training is in chemical and biomolecular engineering.

That does not mean every system is interchangeable. Biological interpretation, instrument behavior, and industrial control each demand their own domain knowledge. The value is in bringing a disciplined modeling approach to those differences.

Abraham Osinuga

The Value Proposition

Translating complex systems into tractable models and actionable insights.

Systems Architecture

Holistic Systems Architecture

Building integrated frameworks that map and analyze complex biological and chemical interactions, from cellular metabolism to ecosystem dynamics.

Digital Twins

Digital Twins

Developing predictive computational replicas of physical and biological processes to run virtual experiments and optimize outcomes without empirical cost.

Precision Control

Precision Control

Applying advanced control theory and process dynamics to stabilize, direct, and optimize system behaviors under uncertainty.

Core Competencies

Systems Biology

  • Genome-Scale Metabolic Modeling
  • Flux Balance Analysis
  • Multi-omics Integration
  • Microbial Community Dynamics

Advanced Process Control

  • Model Predictive Control
  • Process Dynamics
  • PID Tuning & Optimization
  • Industrial Automation

Scientific AI

  • Physics-Informed Neural Networks
  • Machine Learning for Biomarkers
  • Predictive Modeling
  • Time-Series Forecasting

Software & Systems

  • Python, MATLAB, C++
  • High-Performance Computing
  • Agile Software Development
  • Cloud Infrastructure

Research Highlights

CatRange
PNAS Nexus 2026

CatRange

A novel framework for evaluating continuous metabolic states in dynamic environments using advanced sampling techniques.

r-DMFA
iScience 2024

r-DMFA

Regularized Dynamic Metabolic Flux Analysis for inferring dynamic metabolic profiles from sparse time-series measurements.

CorePredX
mSystems 2026

CorePredX

Machine learning integration for predictive modeling of core microbiome functions across environmental gradients.

Graduate Research Assistant

2022 — Present

University of Nebraska–Lincoln | Lincoln, NE, USA

Scientific Software Developer

2020 — 2023

TecGroup GmbH | Germany (Remote)

Process & Compliance Lead

2020 — 2021

Savannah Food Hub | Nigeria

Research Assistant

2020 — 2021

Kyungpook National University | South Korea

Life, Leadership & Global Moments

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Citations · h-index 8 · i10-index 7
15+
Publications
10+
Journals Reviewed
5
Countries Worked Across

Ph.D. in Chemical Engineering · Expected May 2027