Systems Immunology / Multi-Omics
Connecting early immune signals to later antibody trajectories.
DynPertBoost: an unpublished temporal, multi-horizon ensemble framework for pertussis vaccination response.
Unpublished research Question → model → evidence
Conceptual illustration of DynPertBoost: early multi-omics observations inform predictions of antibody responses at later time horizons.
View full figureThe Question
Can early cytokine and gene-expression patterns predict vaccine-induced antibody responses at later timepoints?
My Contribution
Built multi-horizon ensemble integrating cytokine, transcriptomic, and antibody data.
What the record shows
This unpublished work investigates the predictive utility of early-stage multi-omics integration in vaccine response forecasting.
What this does—and does not—establish
Identifies predictive biomarkers but does not directly prove mechanistic causality without further biological validation.